| Entry |
|
|---|
| Name |
Flurazepam (JAN/INN);
Insumin (TN) |
|---|
| Formula |
C21H23ClFN3O
|
|---|
| Exact mass |
387.1514
|
|---|
| Mol weight |
387.8782
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01835 Benzodiazepine sedative-hypnotics
DG03202 Hypnotic
DG01567 GABA-A receptor agonist
|
|---|
| Remark |
| Product (DG00919): | D00695<US> D01408<JP> |
|
|---|
| Efficacy |
Sedative-hypnotic |
|---|
| Comment |
Benzodiazepines
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07230 | GABA-A receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05C HYPNOTICS AND SEDATIVES
N05CD Benzodiazepine derivatives
N05CD01 Flurazepam
D00329 Flurazepam (JAN/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01835 Benzodiazepine sedative-hypnotics
DG00919 Flurazepam
D00329 Flurazepam
DG03202 Hypnotic
DG00919 Flurazepam
D00329 Flurazepam
DG01567 GABA-A receptor agonist
DG00919 Flurazepam
D00329 Flurazepam
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
GABA (ionotropic)
GABR
D00329 Flurazepam (JAN/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01835 Benzodiazepine sedative-hypnotics
DG00919 Flurazepam
DG03202 Hypnotic
DG00919 Flurazepam
DG01567 GABA-A receptor agonist
DG00919 Flurazepam
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 27
1 C2y C 16.4531 -16.9578
2 C8y C 15.6104 -15.8474
3 C8y C 15.9459 -14.4897
4 N1y N 17.2077 -13.9111
5 N2x N 17.8599 -16.9130
6 C5x C 18.4622 -14.5339
7 C1x C 18.7489 -15.9036
8 C8x C 14.9380 -13.5206
9 C8x C 13.5951 -13.9089
10 C8y C 13.2597 -15.2667
11 C8x C 14.2675 -16.2355
12 O5x O 19.5071 -13.5988
13 X Cl 11.8939 -15.6614
14 C8y C 15.8182 -18.2084
15 C8x C 14.4156 -18.2084
16 C8x C 13.7151 -19.4217
17 C8x C 14.4156 -20.6350
18 C8x C 15.8182 -20.6350
19 C8y C 16.5187 -19.4217
20 X F 17.9306 -19.4218
21 C1b C 17.2295 -12.5353
22 C1b C 18.4478 -11.8573
23 N1c N 18.4698 -10.4300
24 C1b C 19.7007 -9.7445
25 C1b C 17.2758 -9.7159
26 C1a C 16.0577 -10.3944
27 C1a C 20.8732 -10.4458
BOND 29
1 3 4 1
2 1 5 2
3 4 6 1
4 2 3 1
5 5 7 1
6 1 2 1
7 6 7 1
8 3 8 2
9 8 9 1
10 9 10 2
11 10 11 1
12 2 11 2
13 6 12 2
14 10 13 1
15 1 14 1
16 14 15 1
17 15 16 2
18 16 17 1
19 17 18 2
20 18 19 1
21 14 19 2
22 19 20 1
23 4 21 1
24 21 22 1
25 22 23 1
26 23 24 1
27 23 25 1
28 25 26 1
29 24 27 1
|
|---|
